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  • Predator Control
    Reply to 140 Suzuki jet vs 150 Yamaha jet
    by Predator Control
    I ended up pulling the trigger on a 150 Yamaha for my heavy 18.5' older Wooldridge Alaskan tunnel with a 3/16" bottom as per recommended by Danny...
    4 minutes ago
  • 4merguide
    Reply to Fauci admits to false positives
    by 4merguide
    Product type: Nucleic acid testing (NAT) technologies that use polymerase chain reaction (PCR) for detection of SARS-CoV-2 Date: 13 January 2021                                                                       WHO-identifier: 2020/5, version 2 Target audience: laboratory professionals and users of IVDs.Purpose of this notice: clarify information previously provided by WHO. This notice supersedes WHO Information Notice for In Vitro Diagnostic Medical Device (IVD) Users 2020/05 version 1, issued 14 December 2020. Description of the problem: WHO requests users to follow the instructions for use (IFU) when interpreting results for specimens tested using PCR methodology.  Users of IVDs must read and follow the IFU carefully to determine if manual adjustment of the PCR positivity threshold is recommended by the manufacturer.WHO guidance Diagnostic testing for SARS-CoV-2 states that careful interpretation of weak positive results is needed (1). The cycle threshold (Ct) needed to detect virus is inversely proportional to the patient’s viral load. Where test results do not correspond with the clinical presentation, a new specimen should be taken and retested using the same or different NAT technology.WHO reminds IVD users that disease prevalence alters the predictive value of test results; as disease prevalence decreases, the risk of false positive increases (2). This means that the probability that a person who has a positive result (SARS-CoV-2 detected) is truly infected with SARS-CoV-2 decreases as prevalence decreases, irrespective of the claimed specificity. Most PCR assays are indicated as an aid for diagnosis, therefore, health care providers must consider any result in combination with timing of sampling, specimen type, assay specifics, clinical observations, patient history, confirmed status of any contacts, and epidemiological information.Actions to be taken by IVD users: Please read carefully the IFU in its entirety. Contact your local representative if there is any aspect of the IFU that is unclear to you. Check the IFU for each incoming consignment to detect any changes to the IFU.Provide the Ct value in the report to the requesting health care provider. Contact person for further information:Anita SANDS, Regulation and Prequalification, World Health Organization, e-mail: rapidalert@who.int References:1. Diagnostic testing for SARS-CoV-2. Geneva: World Health Organization; 2020, WHO reference number WHO/2019-nCoV/laboratory/2020.6.2. Altman DG, Bland JM. Diagnostic tests 2: Predictive values. BMJ. 1994 Jul 9;309(6947):102. doi: 10.1136/bmj.309.6947.102. 
    5 minutes ago
  • Brian M
    Reply to WTB very lightweight sheep rifle
    by Brian M
    "Limited" to 500 yards?

    I get it - long-range shooting is all the rage. And I also understand the tension that one feels when...
    10 minutes ago
  • iofthetaiga
    Reply to Fauci admits to false positives
    by iofthetaiga
    The “Pandemic” of Disinformation in COVID-19
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395797/...
    1 hour ago
  • NorcalBob
    Reply to Fauci admits to false positives
    by NorcalBob
    From: https://mediabiasfactcheck.com/offguardian/
    Know where your information comes from.

    Analysis / Bias

    In review, OffGuardian...
    1 hour ago
  • hunter1951
    Reply to Thinking of buying a sled
    by hunter1951
    I think the electronic reverse sucks, the machine I had with only gave you 45 seconds to backup...
    1 hour ago
  • hunter1951
    Reply to Thinking of buying a sled
    by hunter1951
    stay away from any Polaris 550 fan cool won’t go into problems just google and read...
    2 hours ago
  • Roger45
    Reply to 2020 DM 427 season
    by Roger45
    Isn't this the hunt you drew? How did you do?
    2 hours ago
  • cdubbin
    Reply to Help me direct the dart!
    by cdubbin
    The west is pretty crammed these days....hundreds of thousands of hunters every fall, concentrated on limited public land. There's very few places in...
    3 hours ago
  • 4merguide
    Fauci admits to false positives
    by 4merguide
    3 hours ago

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