So I am thinking about picking up a new rifle for predator hunting, and will serve a dual purpose as a caribou hunting rifle for my wife. My wife is tiny and petite. I was thinking about letting her use my 30-06 next fall for caribou, but I was leaning towards a 243. That way I could use it for predator hunting also. Any suggestions out there? I have also heard of guys using a 22-250 for caribou hunting. I suppose a 223 would also be a good choice. Anybody out there have any suggestion? Thanks.