Because of an eye problem that negates rifle shooting anymore (growl), I have gone to a T/C Encore pistol that will have one of the 15" barrels. I am pondering what cartridge to choose for all-around use. I know that there is a multitude of barrels I can have to use, but I want one for general all-around use. I have settled on several, .460 S&W to shoot 454 Casull in, 338 Federal or possibly 480 Ruger. As a lesser possibility, 7mm-08 or .308 might do. Thought about 44 mag, but have a Redhawk already and wanted something with more ballistic potential from a long barreled pistol. I know there are some who don't care for a single shot, but I'm fine with that. Any opinions or preferences out there? Thanks in advance.