I got to shoot two animals this year with my 300 RUM and 180g etips. Muzzle velocity 3280fps.
The first was a smallish brown bear (about 250-300 pounds) at 220 lasered yards. Heart lungs, clean through like a sack of taters. No bullet recovery. Nice rug.
The second was a 50" bull moose lasered 286 yards. 4 shots to try and anchor him before he took 4 steps into the deep water. Two pass through lungs. One oops at the hind quarter found on the off side skin the other through the neck found on the off side skin.
One bullet weighed 179 grains and the other 180. One bullet was .65 inches in diameter and the other .67.
I am very happy with the etip performance on game and out of my rifle. I get a bit more velocity, less fouling and better accuracy than the Barnes TTSX. Hope this helps. Happy hunting.