Hard to know if this question should be here or in the hunting forum. I may have a chance to visit my son this fall in AK. If plans come together for a Caribou hunt, my weapon will be the TC Encore Pro Hunter pistol in 7mm-08. My son has a choice of Remington 700 in 7mm Mag or Model 1895GS Guide gun in .45/70 so I am not to worried about bear backup.
Since Caribou are considerable larger than the Eastern Whitetail my thoughts are to go with the 150gr bullet. So far I don't reload and haven't seen a heavier factory choice.