I am in WY and our grizzly are getting thick. They are not hunted and are pretty bold. I had an issue with one last year and previously shot a 300wm. I bought a 338 WM this year and love it. I loaded 210 TTSX for hunting and 250 TSX for a defensive round to stop one right now. I shot a bull elk with the 250's at 35 yards quartering away. I shot him in front of the right hip and it came out through the opposing front shoulder twice about 4" apart. He went about 30 yards and was still standing so I put a 210 through the middle of him and he went down. I fully expected him to fall in his tracks on shot 1. I killed another elk this fall with 210 TTSX and it put her down pretty good. I am a big fan of the TTSX. I think the bigger hole in the TTSX hollowpoint opens it up faster and it shocks internally more than the TSX. I talked to one of my buddies that hunts Africa for Buff and everything else and he said he has had similar experiences with the TSX in his 375 H&H and thinks that at close range it pencil holes them. He said for dangerous game and close quarters he likes the partition. I also talked to a PH in Africa and he said the 300 Woodleigh soft, with a blunt point is hard to beat for dangerous game in close quarters. That sounds like a good round to me. But, I want to know what some of you in AK thought would be good for devastating kills on a charging grizzly out of a 338 Win Mag. I reload and am up for building the best round I can. Thanks in advance.