I rifle hunt everything with a .280 remington. The only thing I have killed with it up here is a caribou. I know the popular opinion for an all around alaska gun is "bigger is better" but I can not afford to buy another rifle so the .280 has to kill everything from a sitka black tail to a moose for me. The bullet I have selected for hunting anything up to caribou and black bear sized game is a Hordady 154 grain soft point. I got a pass through on the caribou so it worked pretty good for me. I read that bonded bullets loose anywhere from 20 to 30 percent of their weight when they hit and start to open up so by the time my bullets gets into vitals Im actually hitting that animal with a bullet that can weigh between 100 to 130 grains. My question is this. If I bought higher quality barnes bullets that claim to keep 100 percent of their weight could I hand load 120 grainers to do the task that I used 150 grain bonded bullets to do and get the same if not better penetration? The same goes for moose and grizzly. Could I load a 150 grain barnes tripple shock and expect it to penetrate as well if not better than a 175 grain bonded bullet? Keep in mind with moose and grizzly I do not plan on taking a shot outside of 200 yards and nothing through the shoulders, all shots to be placed behind the shoulder. Thanks for any advice.