Wouldn't a 270 ren be an excellent revolver/lever rifle cartridge? Sure wish some aspiring gunsmith would do this conversion on a revolver, and a rifle. It'd be just like a 22 magnum, only more bullet weight. With hard cast lead bullets, the velocity would be mild enough for small game hunting.
It would be winter rifle perfection IMO. And with all the craze over the 6.8 spc, you'd sure be able to find some great home defense bullets too. In times of sparse rimfire ammo, this would make a viable rimfire alternative.
straightwalling 22 hornet cases to accept a 270 caliber bullet is a dandy idea IMO.